Pefloxacin [Inn-French]
Brand names,
Pefloxacin [Inn-French]
Analogs
Pefloxacin [Inn-French]
Brand Names Mixture
Pefloxacin [Inn-French]
Chemical_Formula
C17H20FN3O3
Pefloxacin [Inn-French]
RX_link
No information avaliable
Pefloxacin [Inn-French]
fda sheet
Pefloxacin [Inn-French]
msds (material safety sheet)
Pefloxacin [Inn-French]
Synthesis Reference
No information avaliable
Pefloxacin [Inn-French]
Molecular Weight
333.358 g/mol
Pefloxacin [Inn-French]
Melting Point
271 oC
Pefloxacin [Inn-French]
H2O Solubility
11.4 mg/mL at 25 oC
Pefloxacin [Inn-French]
State
Solid
Pefloxacin [Inn-French]
LogP
1.49
Pefloxacin [Inn-French]
Dosage Forms
No information avaliable
Pefloxacin [Inn-French]
Indication
For the treatment of uncomplicated gonococcal urethritis in males and for gram-negative-bacterial infections in the gastrointestinal system and the genitourinary tract.
Pefloxacin [Inn-French]
Pharmacology
Pefloxacin is a fluoroquinolone antibiotic. Flouroquinolones such as pefloxacin possess excellent activity against gram-negative aerobic bacteria such as E.coli and Neisseria gonorrhoea as well as gram-positive bacteria including S. pneumoniae and Staphylococcus aureus. They also posses effective activity against shigella, salmonella, campylobacter, gonococcal organisms, and multi drug resistant pseudomonas and enterobacter.
Pefloxacin [Inn-French]
Absorption
Well absorbed by the oral route.
Pefloxacin [Inn-French]
side effects and Toxicity
Adverse reactions include peripheral neuropathy, nervousness, agitation, anxiety, and phototoxic events (rash, itching, burning) due to sunlight exposure.
Pefloxacin [Inn-French]
Patient Information
No information avaliable
Pefloxacin [Inn-French]
Organisms Affected
Enteric bacteria and other eubacteria